Paul Lichtenstein

This study uses genome-wide meta-regression to analyze social behavior across different contexts, ages, and reporters, identifying six genetic loci and showing modest heritability.

This paper conducts a GWAS of subclinical obsessive-compulsive symptoms (OCS) in 33,943 individuals, finding polygenic risk and genetic overlap with OCD.

The paper maps genetic and environmental influences on autistic traits across Sweden and the UK using twin study data, revealing geographical variations in their aetiology.

This study finds ADHD is genetically more closely linked to neurodevelopmental disorders than externalizing or internalizing disorders after accounting for a general psychopathology factor.

This study uses Swedish registry data to predict substance use disorders in ADHD youth with machine learning models, achieving moderate accuracy even without prior SUD diagnosis.

This study investigates the association between rare copy number variants (CNVs) and neurodevelopmental problems (NPs) in children, finding sex-specific effects in anxiety/depression.

The study finds that rare copy number variants (CNVs) contribute to bipolar disorder risk primarily in schizoaffective disorder bipolar type cases, with differences in CNV burden and schizophrenia polygenic risk scores between subtypes.

The paper describes the methods and recruitment strategies of the Anorexia Nervosa Genetics Initiative (ANGI), which successfully enrolled 13,364 individuals with AN and controls for genetic research.

This study evaluates ADHD genetic risk variants' association with general psychopathology and specific neurodevelopmental traits, finding general pleiotropy and a specific link to hyperactivity/impulsivity.

This study finds genetic overlap between adolescent psychotic experiences and schizophrenia, bipolar disorder, and major depression using polygenic risk scores and genome-wide association analyses.

This paper uses transcriptomic imputation to identify gene-tissue associations linked to Anorexia Nervosa risk, finding significant links in both brain and metabolic tissues.

The paper analyzes copy number variations in 100 twin pairs enriched for neurodevelopmental disorders, finding no postzygotic de novo CNVs but higher rates of CNVs overlapping nervous system genes in discordant pairs.

The paper finds genetic correlations between psychiatric disorders and related continuous traits in a Swedish twin sample, suggesting disorders are extreme ends of continuous traits.

This study investigates genetic mechanisms underlying sex bias in ADHD prevalence using genome-wide data and finds no mean polygenic burden difference across sexes but increased risk in female siblings and comorbid conditions.