Jeffrey Alan Golden

Anxiety-associated behaviors following ablation of Miro1 from cortical excitatory neurons

This study ablates Miro1 in cortical excitatory neurons and finds it leads to mitochondrial mislocalization, reduced brain size, and anxiety-like behaviors in adult mice.

ARX regulates cortical interneuron differentiation and migration

This study investigates ARX's role in cortical interneuron development and migration, identifying its regulatory impact on proliferation, fate specification, and cell-cell communication.

Loss of function mutation of mouse Snap29 on a mixed genetic background phenocopy abnormalities found in CEDNIK and 22q11.2 Deletion Syndrome patients

This study shows that a Snap29 loss-of-function mutation on a mixed genetic background in mice replicates multiple abnormalities seen in CEDNIK and 22q11.2DS patients, including skin, neurological, and fertility issues.

A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brain