Lindsay K. Festa

This study shows TRPML1 regulates oligodendrocyte morphology and myelination through actin dynamics and calcium signaling during differentiation.

This study ablates Miro1 in cortical excitatory neurons and finds it leads to mitochondrial mislocalization, reduced brain size, and anxiety-like behaviors in adult mice.

This study shows that bictegravir inhibits oligodendrocyte maturation by causing lysosomal de-acidification, which can be reversed by activating TRPML1.