Anxiety-associated behaviors following ablation of Miro1 from cortical excitatory neurons
Abigail Myers, Madison Sakheim, Cole Rivell, Catherine Fengler, Lindsay K. Festa, Kathy M. Guerra, Layla Jarrahy, Riley Shin, Megan Case, Caroline Chapman, Leah Basel, Slade Springer, Nicholas Kern, Jennifer Gidicsin, Ginam Cho, , Jeffrey Alan Golden
This study ablates Miro1 in cortical excitatory neurons and finds it leads to mitochondrial mislocalization, reduced brain size, and anxiety-like behaviors in adult mice.
eNeuro · Dec 12, 2025Peer-reviewedNeuroscience