Lucas Mora-Quilis

This study shows that phenotypic heterogeneity in Klebsiella pneumoniae affects phage resistance and cocktail efficacy, with acapsular variants being more susceptible to phages and sustaining cocktail effectiveness under selective pressure.

This study shows that coevolution with a phage cocktail reduces reversible phenotypic resistance in K. pneumoniae by forcing mutation-based resistance.

The paper shows that Klebsiella pneumoniae can resist phage infection through reversible downregulation of capsule biosynthesis without genetic mutations.