Author

Nicolas Broguière

École Polytechnique Fédérale de LausanneORCID 0000-0001-9934-4505Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Matthias P. LütolfiD· 3 shared Mehmet GirginiD· 3 shared Alfonso Martínez AriasiD· 1 shared Andrea Boni· 1 shared Bastien Mercier· 1 shared Chulan KwoniD· 1 shared Giuliana RossiiD· 1 shared Lorenzo MattoliniiD· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersDevelopmental Biology

Matthias P. LütolfORCID

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3 papers

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedAug 26, 2021

Bioengineered embryoids mimic post-implantation development in vitro

Mehmet Girgin, Nicolas Broguière, Sylke Hoehnel…·Matthias P. Lütolf

This study develops EpiTS embryoids, which mimic post-implantation development in vitro by combining ESC and TSC aggregates to model gastrulation and axial morphogenesis.

67 citationstop 4%

mouseexperimental assay

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Developmental BiologyStem Cell ReportsPeer-reviewedApr 22, 2021

Gastruloids generated without exogenous Wnt activation develop anterior neural tissues

Mehmet Girgin, Nicolas Broguière, Lorenzo Mattolini, Matthias P. Lütolf

This study develops a method to generate gastruloids with anterior neural tissues by inhibiting WNT signaling in mouse ESCs without exogenous Wnt activation.

83 citationstop 3%

mousebulk RNA-seq

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Developmental BiologyCell stem cellPeer-reviewedNov 10, 2020

Embryonic organoids recapitulate early heart organogenesis

Giuliana Rossi, Nicolas Broguière, Matthew Miyamoto…·Matthias P. Lütolf

This paper demonstrates that mouse embryonic stem cells can generate heart-like structures with in vivo-like morphogenesis, supporting cardiovascular progenitors and early heart field compartments.

306 citationstop 1%

mouseexperimental assay

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