Author

Yan Chun Li

University of ChicagoORCID 0000-0001-9937-7630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Ashley M. SidebottomiD· 1 shared Hardik ShahiD· 1 shared Jie Du· 1 shared Lei Wang· 1 shared Li YiD· 1 shared Lu GaoiD· 1 shared Matthew Odenwald· 1 shared Mengjie CheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Ashley M. SidebottomORCID

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1 paper

Recent·Most cited

PhysiologybioRxivPreprintMay 19, 2026

Gut Microbiota-derived Acetate Safeguards the Colonic Epithelial Acetyl-CoA Reserve to Avert Colonic Senescence

Jie Du, Rajesh Sarkar, Lei Wang…·Yan Chun Li

The paper shows that acetate from gut microbiota maintains acetyl-CoA levels in colonic epithelial cells, preventing age-independent senescence and inflammation.

1 citation

mouseproteomics

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