Genetic & Genomic MedicinemedRxivPreprint
Association of polygenic risk scores with low-density lipoprotein cholesterol levels and control: findings from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Christina G. Selkirk, Tamar Sofer, Brian Spitzer…·Maria Argos
This study evaluates polygenic risk scores (PRS) for LDL cholesterol in a diverse Hispanic/Latino population, finding that some PRS improve prediction across subgroups but statin effectiveness varies with genetic ancestry.
DOI 10.64898/2026.09.16.26363269