Haitao Xiang

IntroSpect improves HLA binding peptide identification sensitivity by 80% using motif-guided database building, while maintaining high accuracy and FDR control.

EPIP predicts MHC-I epitope presentation by integrating mass spectrometry-derived motifs and tissue-specific RNA-seq data, outperforming existing methods in independent validation.

The paper reports the chromosome-level genome of the white-spotted bamboo shark and shows chromosome rearrangements contribute to phenotypic diversity in cartilaginous fishes.