Scott E. Williams

Differential roles of Rad18 in repressing carcinogen- and oncogene-driven mutagenesis in vivo

This study shows Rad18 suppresses 4NQO-induced oral carcinogenesis but not KrasG12D-driven lung tumors, highlighting context-specific tumor-suppressive roles.

Hemidesmosomes regulate epidermal differentiation during embryogenesis

This study shows that hemidesmosomes regulate epidermal differentiation by promoting basal cell retention during embryogenesis through both mitotic and non-mitotic mechanisms.

Ontogeny of the vagal gut-brain axis

The paper identifies the development of a gut-brain circuit involving entero-endocrine cells and vagal neurons, showing its role in feeding and social behavior through BDNF regulation.

AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis

This study shows AGS3 inhibits LGN to regulate spindle orientation, affecting cell division angles and fate decisions in mammalian epidermis.