Gaith N. Droby

This paper identifies CD73 as a regulator that limits oncogenic activity of mutant β-catenin in endometrial carcinomas, showing that its loss increases transcriptional activity and tumor progression.

This study shows Rad18 suppresses 4NQO-induced oral carcinogenesis but not KrasG12D-driven lung tumors, highlighting context-specific tumor-suppressive roles.

This study identifies RNF25's role in protecting DNA replication forks from degradation, independent of its ubiquitin signaling functions.

This study identifies TRIP13 as a key factor protecting KRAS-mutant pancreatic cancer cells from DNA replication stress and therapy-induced damage.

This study identifies MAPK14/p38α as critical for HGEC spheroid growth, shaping its transcriptomic, proteomic, and metabolomic landscapes and promoting tumorigenic properties.

The paper identifies CG2941 as a Gemin4 ortholog in Drosophila melanogaster and shows its essential role in organismal viability.