Nan Wang

This study shows that aggressive cholesterol lowering halts atherosclerosis progression and promotes plaque stabilization in Jak2V617F mice by reversing inflammasome activation and increasing pro-resolving macrophage features.

This study shows that IL-18 inhibition increases atherosclerosis lesions and necrotic cores in Jak2V617F clonal hematopoiesis mice, despite improving fibrous cap thickness.