Author
University Medical Center UtrechtORCID 0000-0001-9983-204XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Chen Eitan, Aviad Siany, Elad Barkan…·Eran Hornstein
The paper identifies non-coding variants in the IL18RAP 3'UTR that reduce ALS risk by modulating neuro-inflammation through NF-κB signaling in microglia.
Rick A. A. van der Spek, Wouter van Rheenen, Sara L. Pulit…·on behalf of the Project MinE ALS Sequencing Consortium
The paper introduces a data browser for Project MinE, providing open-access whole-genome sequencing data from ALS patients and controls to support research without requiring advanced bioinformatics skills.
Bojian Yin, Marleen Balvert, Rick A. A. van der Spek…·Alexander Schönhuth
This paper develops a deep learning approach to predict ALS from genotype by leveraging genome structure, showing better performance than other methods.
Wouter van Rheenen, Sara L. Pulit, Annelot M. Dekker…·Jan Herman Veldink
Project MinE analyzes whole-genome sequencing data from ALS patients and controls to study genetic variation and its implications for disease susceptibility.