Odessa Yabut

This study identifies FGF5 signaling as a key driver in SHH subgroup infantile medulloblastoma, showing its upregulation and therapeutic potential through FGFR inhibition.

The paper shows that SHH signaling modulates FGF15 expression to maintain neocortical progenitor specification during corticogenesis.

This study shows that Sufu deletion in neural progenitors causes increased proliferation and reduced survival of stem/precursor cells in the dorsal V-SVZ via a Gli3-dependent mechanism.