NeurosciencebioRxivPreprint
Distinct sub-cellular autophagy impairments occur independently of protein aggregation in induced neurons from patients with Huntington's disease
Karolina Pircs, Janelle Drouin‐Ouellet, Jeovanis Gil…·Johan Jakobsson
This study shows that induced neurons from Huntington's disease patients have impaired autophagy in neurites, independent of protein aggregation, and that HTT is critical for neuronal autophagy.
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