Author

Isabelle St‐Amour

Centre hospitalier de l'Université LavalORCID 0000-0003-2042-804XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Johan JakobssoniD· 2 shared Karolina PircsiD· 2 shared Sébastien S. HébertiD· 2 shared A Loiselle· 1 shared Behnaz NateghiiD· 1 shared Bob A. HersbachiD· 1 shared Chantelle F. SephtoniD· 1 shared Daniela A. GrassiiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Johan JakobssonORCID

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2 papers

Recent·Most cited

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedJul 22, 2022

Widespread alterations in microRNA biogenesis in human Huntington's disease putamen

Séréna Petry, Rémi Keraudren, Behnaz Nateghi…·Sébastien S. Hébert

This study investigates miRNA biogenesis defects in HD brain tissue, finding downregulation of key enzymes and maturation defects, primarily in the striatum.

21 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 1, 2021

Distinct sub-cellular autophagy impairments occur independently of protein aggregation in induced neurons from patients with Huntington's disease

Karolina Pircs, Janelle Drouin‐Ouellet, Jeovanis Gil…·Johan Jakobsson

This study shows that induced neurons from Huntington's disease patients have impaired autophagy in neurites, independent of protein aggregation, and that HTT is critical for neuronal autophagy.

3 citations

humanexperimental assay

𝕏 PostBluesky