The CD4 T cell-independent IgG response during persistent virus infection favors emergence of neutralization-escape variants
Katelyn Nicole Ayers, Matthew D. Lauver, Kalynn M Alexander, Ge Jin, Kitt D. Paraiso, Alyssa Ochetto, Sonal Garg, Daniel J. Goetschius, Susan L. Hafenstein, Joseph Che‐Yen Wang, Aron E. Lukacher
Pre-existing and acquired CD4 T cell deficiency facilitates outgrowth of Ab-escape viral variants during persistent infection.
bioRxiv · Dec 22, 2024 · PreprintImmunology