Graciely Gomes Corrêa

The paper engineers a glucose-inducible genetic circuit in Bacillus subtilis to maintain production capacity during scale-up by switching metabolic states, improving industrial production efficiency.

This study characterizes five purine riboswitches in both in vitro and in vivo systems, identifying transcription pause sites and correlating readthrough with gene expression.

This paper designs synthetic small RNAs to target bacterial riboswitches, enhancing gene expression up to 103-fold and improving riboflavin production in engineered strains.