Author

Maria Bykhovskaia

Wayne State UniversityORCID 0000-0002-0020-9715Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

J. Troy LittletoniD· 1 shared Zhuo Guan· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperNeuroscience

J. Troy LittletonORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 18, 2026

Disease-causing mutations in Synaptotagmin can act via dominant-negative, gain-of-function or haploinsufficient mechanisms

Zhuo Guan, Maria Bykhovskaia, J. Troy Littleton

The paper investigates how disease-causing mutations in Synaptotagmin affect synaptic transmission through different mechanisms in a Drosophila model.

DOI 10.64898/2026.03.17.712223

Drosophilaexperimental assay

𝕏 PostBluesky

BiophysicsBiophysical JournalPeer-reviewedSep 10, 2024

Dynamic Formation of the Protein-Lipid Pre-fusion Complex

Maria Bykhovskaia

This study uses molecular dynamics to model the dynamic formation of the pre-fusion protein-lipid complex involving Syt1, SNARE, and Cpx, revealing conformational transitions and the role of Syt1-Cpx interactions.

3 citations

protein structuredeep learning

𝕏 PostBluesky