Benjamin R. Lichman

This study identifies and reconstitutes the biosynthetic pathway for Securinega alkaloids in Flueggea suffruticosa, revealing a connection to cyanogenic glucoside biosynthesis.

This study shows bidirectional horizontal gene transfer between maize and Zuloagaea bulbosa, with horizontally transferred genes enriched in biosynthetic gene clusters.

This paper reconstructs the complete nicotine biosynthesis pathway in vitro and in planta, identifying key enzymes and providing structural insights.

This study identifies artemether and EFL9 as inhibitors of kynurenine production through distinct mechanisms, offering potential new therapeutic approaches for targeting tryptophan metabolism.

This study identifies OLADOs, a new class of eukaryotic decarboxylases involved in alkaloid biosynthesis, showing their parallel evolution from bacterial-like enzymes.

The paper investigates how three cytochrome P450 enzymes in Catharanthus roseus transform 19E-geissoschizine into four distinct alkaloid scaffolds through oxidative transformations.

The paper identifies two CYP450 enzymes in Tabernanthe iboga responsible for oxidative modifications of tabersonine scaffolds using a streamlined screening strategy in Nicotiana benthamiana.

The paper presents genome assemblies for two Nepetoideae species and provides a species tree using genome-derived gene models.