Andrew Care

This study shows that modular PEGylation of encapsulin nanocages reduces macrophage uptake and extends circulation time in mice.

The paper engineers a bacterial encapsulin into a nanoscaffold for controlled antigen display, demonstrating its utility in generating single- and multi-target nanovaccines for Alzheimer's disease.

This paper describes an in vitro method for packaging synthetic cargo into encapsulin protein cages with high fidelity and broad compatibility, outperforming in cellulo assembly.

This study evaluates how protein coronas from cerebrospinal fluid affect nanoparticle interactions with brain cells, finding that CSF-derived coronas enhance these interactions.

The paper describes the development of a light-responsive encapsulin nanoreactor that generates reactive oxygen species for photodynamic therapy.