Wei Deng

This study develops a light-responsive lipid nanoparticle platform for VEGFA gene editing to suppress choroidal neovascularisation, showing reduced vascular leakage and structural abnormalities in a rat model.

This paper introduces a CRISPR/Cas tandem biosensing system for ultrasensitive DNA detection without pre-amplification, achieving 1 aM sensitivity and distinguishing cancer mutations in CRC mice.

This study evaluates how protein coronas from cerebrospinal fluid affect nanoparticle interactions with brain cells, finding that CSF-derived coronas enhance these interactions.