Author

Rezwan Siddiquee

The University of SydneyORCID 0000-0002-7893-3201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Alex LoustauiD· 2 shared Taylor N. SzyszkaiD· 2 shared Yu Heng LauiD· 2 shared Andrew CareiD· 1 shared Carol H. PongiD· 1 shared Claire RennieiD· 1 shared Felicia Lie· 1 shared Lachlan S. R. AdamsoniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersEvolutionary Biology

Alex LoustauORCID

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3 papers

Recent·Most cited

Directed evolution of multimeric proteins is enabled by dual-compensatory gene duplication

Rezwan Siddiquee, Felicia Lie, Taylor N. Szyszka, Alex Loustau, Michael P. Andreas, Tobias W. Giessen, Yu Heng Lau

This paper introduces a directed evolution strategy for multimeric proteins using gene duplication to enable the selection of diverse high-performing variants.

bioRxiv · Jan 12, 2026 · PreprintEvolutionary Biology

High-fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages

Taylor N. Szyszka, Rezwan Siddiquee, Alex Loustau, Lachlan S. R. Adamson, Claire Rennie, Tiancheng Huang, Reginald Young, Andrew Care, Yu Heng Lau

This paper describes an in vitro method for packaging synthetic cargo into encapsulin protein cages with high fidelity and broad compatibility, outperforming in cellulo assembly.

Angewandte Chemie International Edition · Mar 26, 2025Peer-reviewedBiochemistry

A programmable seeker RNA guides target selection by IS1111 and IS110 type insertion sequences.

Rezwan Siddiquee, Carol H. Pong, Ruth M. Hall, Sandro F. Ataide

The paper identifies a seeker RNA derived from the NCR of IS1111 and IS110 insertion sequences that guides target site selection during transposition.

Nature Communications · Jun 19, 2024Peer-reviewedMicrobiology