Author

Paolo G.V. Martini

Moderna Therapeutics (United States)ORCID 0000-0002-0051-797XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:multiome· 1

Frequent Co-Authors

Andrea FrassettoiD· 3 shared Alex CavedoniD· 2 shared Dany P.B. PerocheauiD· 2 shared Julien BaruteauiD· 2 shared Lisa M. Rice· 2 shared Loukia Touramanidou· 2 shared Patrick F. FinniD· 2 shared Paul GisseniD· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Andrea FrassettoORCID

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3 papers

Recent·Most cited

Molecular BiologyTranslational Vision Science & TechnologyPeer-reviewedJul 9, 2024

Lipid nanoparticle-mediated delivery of mRNA into the mouse and human retina and other ocular tissues.

C. Chambers, Gillian L. Soo, Abbi L. Engel…·Timothy J. Cherry

This paper demonstrates reliable mRNA delivery via lipid nanoparticles to specific retinal cells in mice and human ocular tissues without significant inflammation.

36 citationstop 3%

mousehuman

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Molecular BiologybioRxivPreprintJul 26, 2023

Macrophage inhibitor clodronate enhances liver transduction of lentiviral but not AAV vectors or mRNA lipid nanoparticles in vivo.

Loukia Touramanidou, Sonam Gurung, Andrei Claudiu Cozmescu…·Julien Baruteau

This study shows that clodronate liposomes enhance lentiviral liver transduction but not AAV or LNP-mRNA in mice.

DOI 10.1101/2023.07.26.550697

mousemultiome

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GeneticsbioRxivPreprintOct 19, 2022

mRNA therapy restores ureagenesis and corrects glutathione metabolism in argininosuccinic aciduria

Sonam Gurung, Oskar Vilhelmsson Timmermand, Dany P.B. Perocheau…·Julien Baruteau

This study shows that mRNA therapy restores ureagenesis and glutathione metabolism in ASL-deficient mice, correcting liver disease and neurocognitive impairments.

10 citations

mousemetabolomics

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