Author

Diego J. Rodriguez

Broad InstituteORCID 0000-0002-0053-8674Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Aaliyah Washington· 1 shared Adel Atari· 1 shared Alberto VidesiD· 1 shared Alessandro Sinopoli· 1 shared Alexander I. SpiraiD· 1 shared Antonio Cuevas-NavarroiD· 1 shared Aparna HegdeiD· 1 shared Arvin C. DariD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Aaliyah Washington

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 24, 2025

Mechanisms of resistance to active state selective tri-complex RAS inhibitors

Ben Sang, Ling Feng Ye, Feng Hu…·Piro Lito

This study identifies mechanisms of resistance to tri-complex RAS inhibitors in patients with RAS-driven cancers, showing that resistance alterations disrupt the RAS:drug:CYPA tri-complex formation.

12 citations

humanDNA methylation

Cancer BiologyJournal of Clinical InvestigationPeer-reviewedFeb 27, 2025

Identification of potent biparatopic antibodies targeting FGFR2 fusion driven cholangiocarcinoma.

Saireudee Chaturantabut, Sydney Oliver, Dennie Tompers Frederick…·William R. Sellers

The paper identifies biparatopic antibodies targeting FGFR2 extracellular domain that effectively block FGFR2 fusion-driven cholangiocarcinoma signaling and growth.

5 citations

humanproteomics