Functional Plasticity in Chromosome-Microtubule Coupling on the Evolutionary Time Scale
Sundar Ram Sankaranarayanan, Satya Dev Polisetty, Kuladeep Das, Arti Baban Dumbrepatil, Bethan Medina‐Pritchard, Martin R. Singleton, A. Arockia Jeyaprakash, Kaustuv Sanyal
The paper identifies a conserved arginine residue in the Dam1 complex subunit Dad2 that is essential for viability in yeast but less so in fungi with regional centromeres, suggesting functional plasticity in chromosome-microtubule coupling.
Life Science Alliance · Oct 4, 2023Peer-reviewedGenetics