Author

Mateusz Sypniewski

Poznań University of Life SciencesORCID 0000-0002-0108-0255Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian LejmaniD· 1 shared Agnieszka PawlakiD· 1 shared Alicja JozkowicziD· 1 shared Alicja WoźnaiD· 1 shared Anna Bodora-Troińska· 1 shared Anna KusienickaiD· 1 shared Artur ZaczyńskiiD· 1 shared Daria Kołodziejska· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Adrian LejmanORCID

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2 papers

Recent·Most cited

Non-Canonical Heme Oxygenase-1 Function in Hematopoietic Stem Cell Homeostasis and Aging

Monika Żukowska, Izabella Skulimowska, Mateusz Sypniewski, Anna Kusienicka, Mateusz Tomczyk, Sylwester Mosiołek, Jan Morys, Ewa Werner, Karolina Hajduk, Dounia Djeghloul, Michèle Goodhardt, Józef Dulak, Alicja Jozkowicz, Krzysztof Szade

This study shows that HO-1 has a non-canonical, cell-intrinsic role in regulating HSC homeostasis, differentiation, and aging by affecting genome maintenance, apoptotic signaling, and RNA metabolism.

bioRxiv · Jan 28, 2026 · PreprintCell Biology

The Thousand Polish Genomes Project- a national database of Polish variant allele frequencies

Elżbieta Kaja, Adrian Lejman, Dawid Sielski, Mateusz Sypniewski, Tomasz Gambin, Mateusz Dawidziuk, Tomasz Suchocki, Paweł Golik, Marzena Liliana Wojtaszewska, Magdalena Mroczek, Maria Stępień, Joanna Szyda, Karolina Lisiak-Teodorczyk, Filip Wolbach, Daria Kołodziejska, , Paweł Sztromwasser

The paper describes the creation of a national database of Polish genomic variant allele frequencies using 1,079 whole genomes, identifying rare variants and confirming allele frequencies for known pathogenic variants.

International Journal of Molecular Sciences · Apr 20, 2022Peer-reviewedGenomics