Non-Canonical Heme Oxygenase-1 Function in Hematopoietic Stem Cell Homeostasis and Aging
Monika Żukowska, Izabella Skulimowska, Mateusz Sypniewski…·Krzysztof Szade
This study shows that HO-1 has a non-canonical, cell-intrinsic role in regulating HSC homeostasis, differentiation, and aging by affecting genome maintenance, apoptotic signaling, and RNA metabolism.