Author

Xiang Gao

Model Animal Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Developmental Biology· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:imaging· 3 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Arupratan DasiD· 1 shared Bo SheniD· 1 shared Christopher WardiD· 1 shared Chuang TaniD· 1 shared Chuankai Chen· 1 shared Clare Norris· 1 shared Dale Pimm· 1 shared David Pajuelo RegueraiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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1 shared paperNeuroscience

Arupratan DasORCID

Author profile →

5 papers

Recent·Most cited

5-HT1A Antagonist WAY-100635 Prevents Chronic Neurodegeneration and Immune Activation After TBI

Sayanta Dutta, Lilesh Kumar Pradhan, Jie Chen, Nian Wang, Xiang Gao, Arupratan Das

This study shows that WAY-100635, a 5-HT1A antagonist, reduces chronic neurodegeneration and immune activation after TBI by preserving neurons, synapses, and visual function.

bioRxiv · Oct 12, 2026 · PreprintNeuroscience

Stem cell factor acts locally in the bone marrow to promote stem and progenitor cell maintenance

Maria Angelica Freitas-Cortez, Stefano Comazzetto, Xiang Gao, Bo Shen, Lei Ding, Zhiyu Zhao, Sean J. Morrison

This study shows that SCF produced locally in bone marrow stromal and endothelial cells supports hematopoietic stem and progenitor cell maintenance, while systemic SCF does not.

bioRxiv · Sep 29, 2026 · PreprintCell Biology

Establishing Comprehensive Transthoracic Echocardiography Reference Ranges for Mouse Models: Insights into the Impact of Anesthesia, Sex, and Age

Manuela A. Oestereicher, Christopher Ward, Elida Schneltzer, Susan Marschall, Helmut Fuchs, Valérie Gailus‐Durner, Ghina Bou About, Mohammed Selloum, Hamid Méziane, Michelle E. Stewart, Lydia Teboul, Clare Norris, Dale Pimm, Marina Kan, Federico Lopez Gomez, , Nadine Spielmann

This study establishes TTE reference ranges for mice, showing anesthesia significantly affects cardiac function, with minimal sex differences and modest age-related changes.

bioRxiv · Apr 14, 2025 · PreprintGenetics

Angiocrine FSTL1 insufficiency leads to atrial and vein wall fibrosis via SMAD3 activation

Haijuan Jiang, Luqing Zhang, Xuelian Liu, Wei Sun, Katsuhiro Kato, Chuankai Chen, Xiao Li, Taotao Li, Zhiliang Sun, Wencan Han, Fujing Zhang, Qi Xiao, Zhongzhou Yang, Junhao Hu, Zhihai Qin, , Yulong He

This study shows that loss of endothelial FSTL1 causes atrial and vein wall fibrosis through SMAD3 activation, leading to heart failure.

Arteriosclerosis Thrombosis and Vascular Biology · Feb 13, 2020Peer-reviewedDevelopmental Biology

Transcription Factor Regulation of RNA polymerase’s Torsional Capacity

Jie Ma, Chuang Tan, Xiang Gao, Robert M. Fulbright, Jeffrey W. Roberts, Michelle D. Wang

This study shows that the transcription factor GreB enhances RNA polymerase's torsional capacity by reducing backtracking and increasing torque generation by 65%.

bioRxiv · Apr 23, 2018 · PreprintBiophysics