Author

Anna Katharina Schlusche

University of CologneORCID 0000-0002-0111-665XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Achim TreschiD· 1 shared Adam FrankishiD· 1 shared Ahmed Essam MahfouziD· 1 shared Alexander N. SteiniD· 1 shared Andrey D. PrjibelskiiD· 1 shared Anoushka JoglekariD· 1 shared Ashley Hayes· 1 shared August Benjamin SmitiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Achim TreschORCID

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2 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedAug 24, 2021

Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice

Anna Katharina Schlusche, Sabine Ulrike Vay, Niklas Kleinenkuhnen…·Dirk Isbrandt

This study shows that HCN-channel dysfunction in neural progenitors causes microcephaly by disrupting cell cycle progression and proliferation in mice.

11 citations

mouserat

NeuroscienceNature CommunicationsPeer-reviewedJan 19, 2021

Cell-type, single-cell, and spatial signatures of brain-region specific splicing in postnatal development

Anoushka Joglekar, Andrey D. Prjibelski, Ahmed Essam Mahfouz…·Hagen Tilgner

The paper identifies brain-region specific splicing patterns at single-cell and spatial resolution in postnatal mice, revealing cell-type specific and region-specific isoform expression.

229 citationstop 1%

mouselong-read sequencing