Juan Carlos Boffi

High-throughput serial two-photon tomography with BakingTray and BrainSaw

The paper introduces BakingTray, an open-source software platform for block-face serial two-photon tomography, demonstrating its utility in neuroscience applications.

Central infusion of prostaglandin E2 reveals a unified representation of sickness in the mouse insular cortex

This study shows that PGE2 induces a sickness-like state in mice, with the insular cortex encoding integrated sickness signals better than the somatosensory cortex.

Column-Like Subnetwork Reconstruction in Motor Cortex from Graph-Based 3D High-Density Two-Photon Calcium Imaging

The paper reconstructs functional connectivity in the mouse motor cortex using 3D two-photon calcium imaging and identifies column-like subnetworks with specific connectivity patterns and information flow.

Chemigenetic far-red labels and Ca2+ indicators optimized for photoacoustic imaging.

This paper develops chemigenetic labels and calcium sensors optimized for photoacoustic imaging, showing improved performance in tissue-mimicking phantoms and in vivo applications.

Noisy neuronal populations effectively encode sound localization in the dorsal inferior colliculus of awake mice

The paper shows that noisy neuronal populations in the dorsal inferior colliculus of awake mice encode sound location with decoding accuracy matching mouse discrimination ability.

Primary motor cortex activity traces distinct trajectories of population dynamics during spontaneous facial motor sequences in mice

The paper shows that primary motor cortex population dynamics differ across spontaneous facial motor sequences in mice, suggesting distinct population dynamics codes for different motor sequences.

KCC2-dependent Steady-state Intracellular Chloride Concentration and pH in Cortical Layer 2/3 Neurons of Anesthetized and Awake Mice

The paper measures intracellular chloride concentration and pH in cortical neurons of mice under anesthesia and wakefulness, finding KCC2 is essential for maintaining low [Cl-]i.