Johannes Knabbe

This paper describes a genetic engineering approach for cell type-specific silencing and in vivo imaging of neuronal responses.

The paper identifies neuronal loss in the secondary motor cortex as a mechanism underlying chronic neuropathic pain using longitudinal in vivo imaging.

The paper introduces NuCLear, a method combining in vivo two-photon imaging and deep learning to monitor tissue composition over time in mice brains.

The paper identifies acute and lasting molecular, cellular, and behavioral changes in mice after single-dose ethanol intoxication using proteomics and imaging.

The paper correlates grey matter volume changes with cellular metrics in mice using MRI and in vivo imaging.

This study shows that acute ethanol intoxication causes loss of presynaptic boutons without mitochondria in mice, potentially explaining memory impairments.

The paper visualizes and quantifies dense core vesicle (DCV) trafficking in axons of anesthetized and awake mice, finding faster maximal speeds and lower pausing fraction in vivo compared to in vitro studies.

The paper measures intracellular chloride concentration and pH in cortical neurons of mice under anesthesia and wakefulness, finding KCC2 is essential for maintaining low [Cl-]i.