Author

Leonel Tadao Takada

Broad InstituteORCID 0000-0002-0121-9253Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Agustín M. IbáñeziD· 1 shared Alexandra R. Levine· 1 shared Andrea SlachevskyiD· 1 shared Andrew SingletoniD· 1 shared Bruce L. MilleriD· 1 shared Caroline B. PantazisiD· 1 shared Caroline JonsoniD· 1 shared Christiane StehmanniD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Agustín M. IbáñezORCID

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Author profile →

2 papers

Recent·Most cited

Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations

Juliana Acosta‐Uribe, Stefanie Danielle Piña‐Escudero, J. Nicholas Cochran, Jared W. Taylor, Patricia A. Castruita, Caroline Jonson, Erin A. Barinaga, Kevin Roberts, Alexandra R. Levine, Dawwod S. George, José Alberto Ávila‐Funes, María I. Behrens, Martin Alejandro Bruno, Luis Ignacio Brusco, Nilton Custodio, , Jennifer S. Yokoyama

This study identifies genetic variants associated with Alzheimer's disease and frontotemporal dementia in admixed Latin American populations using whole-genome sequencing and ancestry analysis.

npj Dementia · Jan 21, 2026Peer-reviewedGenetic & Genomic Medicine

Age of onset in genetic prion disease and the design of preventive clinical trials

Eric Vallabh Minikel, Sonia M. Vallabh, Margaret C. Orseth, Jean‐Philippe Brandel, Stéphane Haı̈k, Jean Laplanche, Inga Zerr, Piero Parchi, Sabina Capellari, Jiri Safar, Janna Kenny, Jamie C Fong, Leonel Tadao Takada, Claudia Ponto, Péter Hermann, , Simon Mead

This paper quantifies the challenges of designing preventive clinical trials for genetic prion disease due to high variability in age of onset, suggesting the need for biomarker-based trials.

Neurology · Jun 6, 2019Peer-reviewedNeuroscience