Jinglong Wang

ATM and 53BP1 regulate alternative end joining-mediated V(D)J recombination

This study identifies the role of ATM and 53BP1 in regulating alternative end joining-mediated V(D)J recombination by analyzing repair outcomes of RAG1/2-initiated DSBs.

DNA-PKcs Suppresses Illegitimate Chromosome Rearrangements

This study shows DNA-PKcs inhibition increases chromosome translocations in human cells and shifts repair mechanisms toward MMEJ, similar to mice, highlighting its role in suppressing illegitimate rearrangements.

Shifted PAMs generate DNA overhangs and enhance SpCas9 post-catalytic complex dissociation

The paper shows that shifting the RNA:DNA hybrid relative to the PAM in SpCas9 generates DNA overhangs and accelerates complex dissociation after cleavage.

The role of swnR gene on the biosynthesis pathway of the swainsonine in Metarhizium anisopliae

This study investigates the role of the swnR gene in swainsonine biosynthesis in Metarhizium anisopliae by knocking it out and measuring swainsonine levels.