Author

Marie Le Bouteiller

Stanford MedicineORCID 0000-0002-4149-8488Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Richard L. FrockiD· 3 shared Cheyenne SadeghiiD· 2 shared Adam Yongxin YeiD· 1 shared Amy S. YuiD· 1 shared Anushka Edlabadkar· 1 shared Billy W. LooiD· 1 shared Brianna C. LauiD· 1 shared Charles L. LimoliiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Richard L. FrockORCID

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3 papers

Recent·Most cited

ATM and 53BP1 regulate alternative end joining-mediated V(D)J recombination

Jinglong Wang, Cheyenne Sadeghi, Long V. Le, Marie Le Bouteiller, Richard L. Frock

This study identifies the role of ATM and 53BP1 in regulating alternative end joining-mediated V(D)J recombination by analyzing repair outcomes of RAG1/2-initiated DSBs.

Science Advances · Jul 31, 2024Peer-reviewedMolecular Biology

FLASH-RT does not affect chromosome translocations and junction structures beyond that of CONV-RT dose-rates

Paul G. Barghouth, Stavros Melemenidis, Pierre Montay‐Gruel, Jonathan Ollivier, Vignesh Viswanathan, Patrik Gonçalves Jorge, Luis Antonio Cruz Soto, Brianna C. Lau, Cheyenne Sadeghi, Anushka Edlabadkar, Richard Zhang, Ning Ru, Janet E. Baulch, Rakesh Manjappa, Jinghui Wang, , Richard L. Frock

This study shows FLASH-RT and CONV-RT produce similar levels and proportions of chromosome translocations and junction structures under various oxygen conditions.

Radiotherapy and Oncology · Nov 1, 2023Peer-reviewedMolecular Biology

Ku70 suppresses alternative end-joining in G1-arrested progenitor B cells

Zhuoyi Liang, Vipul Kumar, Marie Le Bouteiller, Jeffrey Zurita, Josefin Kenrick, Sherry G. Lin, Jiangman Lou, Jianqiao Hu, Adam Yongxin Ye, Cristian Boboilă, Frederick W. Alt, Richard L. Frock

The paper shows that Ku70 suppresses alternative end-joining (A-EJ) in G1-arrested progenitor B cells, directing DSB repair toward classical nonhomologous end-joining (C-NHEJ) and preventing translocations.

Proceedings of the National Academy of Sciences · May 18, 2021Peer-reviewedGenetics