Terence R. Strick

The paper investigates competition between glycine and GABA receptors for gephyrin at inhibitory synapses using single-molecule techniques and molecular tweezers, revealing thermodynamic properties and implications for synaptic plasticity.

This study uses single-molecule techniques to show that SARS-CoV-2 spike protein RBD dynamics modulate ACE2 binding through conformational selection without affecting unbinding.

The paper shows that shifting the RNA:DNA hybrid relative to the PAM in SpCas9 generates DNA overhangs and accelerates complex dissociation after cleavage.

This study identifies the mechanism of transcription start site (TSS) selection by bacterial RNA polymerase (RNAP) through experimental assays showing DNA scrunching and antiscrunching.