Author

Sofia N. Nyström

Linköping UniversityORCID 0000-0002-0145-4966Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Cecilia SvanbergiD· 2 shared Esaki Muthu ShankariD· 2 shared Francis R. HopkinsiD· 2 shared Marie LarssoniD· 2 shared Adriana Araceli Becerril-CamposiD· 1 shared Amanda BækiD· 1 shared András HaraziniD· 1 shared Åsa Nilsdotter‐AugustinssoniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

Cecilia SvanbergORCID

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Author profile →

3 papers

Recent·Most cited

Dynamic Responses to an Inflammatory Challenge Distinguish Metabolic Health Across Lean and Obese Individuals

Saeideh Tavajoh, Bianca E Suur, Madison Clark, Adriana Araceli Becerril-Campos, Elia Velasco, Brigita Medelytė, Line Boel Nørregaard, Stine Julie Tingskov, Amanda Bæk, Lykke Moran Skaarup, Erik Schröder, Maryam Dost, Sigrid Bjerge Gribsholt, Jens Meldgaard Bruun, Marianne Quiding‐Järbrink, , Emma Börgeson

This study shows that dynamic inflammatory responses, not static measures, better distinguish metabolic health across lean and obese individuals.

bioRxiv · Sep 18, 2026 · PreprintImmunology

Altered DNA methylation pattern contributes to differential epigenetic immune signaling in the upper respiratory airway of COVID-19 patients

Melissa Govender, Jyotirmoy Das, Francis R. Hopkins, Cecilia Svanberg, Johan Nordgren, Marie Hagbom, Jonas Klingström, Åsa Nilsdotter‐Augustinsson, Yean Kong Yong, Vijayakumar Velu, Sivadoss Raju, Johanna Sjöwall, Esaki Muthu Shankar, Sofia N. Nyström, Marie Larsson

This study identifies altered DNA methylation patterns in the upper respiratory airway of COVID-19 patients, highlighting changes in immune-related genes and potential implications for airway health.

Cells · Oct 27, 2025Peer-reviewedMicrobiology

HIV-1 derived replication intermediates/oligonucleotides induce a type I IFN-dependent immune suppression via STING activation that can be restored by targeting IFNARI

Cecilia Svanberg, Ravi Prasad Mukku, Özkan Besler, Francis R. Hopkins, Christopher Sjöwall, Sofia N. Nyström, Esaki Muthu Shankar, Marie Larsson

This study shows HIV-1-derived oligonucleotides activate STING and type I IFN signaling in dendritic cells, leading to immune suppression that can be reversed by targeting IFNAR1 with Anifrolumab.

bioRxiv · Feb 17, 2025 · PreprintImmunology