Marie Larsson

Genomic Evolution of SARS-CoV-2 Delta Variants Pre- and Post-Omicron Emergence using Alignment-free Machine Learning models

This study uses alignment-free machine learning to analyze SARS-CoV-2 Delta variant spike gene sequences before and after Omicron, identifying genomic changes and distinguishing the two groups with high accuracy.

Altered DNA methylation pattern contributes to differential epigenetic immune signaling in the upper respiratory airway of COVID-19 patients

This study identifies altered DNA methylation patterns in the upper respiratory airway of COVID-19 patients, highlighting changes in immune-related genes and potential implications for airway health.

HIV-1 derived replication intermediates/oligonucleotides induce a type I IFN-dependent immune suppression via STING activation that can be restored by targeting IFNARI

This study shows HIV-1-derived oligonucleotides activate STING and type I IFN signaling in dendritic cells, leading to immune suppression that can be reversed by targeting IFNAR1 with Anifrolumab.