Vijayakumar Velu

This study uses alignment-free machine learning to analyze SARS-CoV-2 Delta variant spike gene sequences before and after Omicron, identifying genomic changes and distinguishing the two groups with high accuracy.

This study shows that IL-6 restricts pre-thymic T cell lineage commitment in SIV-infected rhesus macaques, contributing to loss of viral control.

This study identifies altered DNA methylation patterns in the upper respiratory airway of COVID-19 patients, highlighting changes in immune-related genes and potential implications for airway health.

This paper develops a 3D bioplatform to screen host-directed therapeutics for tuberculosis, identifying compounds that reduce mycobacterial burdens and granuloma lesions.

This study improves NK cell transfer models in mice by showing that CRISPR-generated JAXBoy NK cells persist better than conventional BoyJ cells, and identifies roles for CXCR3 and ASCL2 in splenic NK cell localization during virus infection.