Qing‐Yuan Sun

This study shows maternal obesity causes oocyte genome hyper-methylation via increased DNMTs, which can be partially transmitted to F2 offspring, and melatonin reduces this hyper-methylation through the cAMP/PKA/CREB pathway.

This study builds a spatiotemporal and single-cell atlas of mouse ovary development, identifying novel cell types and regulatory factors in ovarian differentiation.

This study shows that SRSF10 regulates alternative splicing in progenitor spermatogonia, essential for their expansion and spermatogenesis.

This study shows SRSF2 is essential for mRNA splicing and spermatogenesis, with its deletion causing infertility and disrupting key developmental processes.

The paper shows that improving gut microbiota with alginate oligosaccharide enhances semen quality in type 1 diabetes by increasing n-3 PUFA and improving metabolic and immune functions.

This study uses single-cell RNA sequencing to analyze fetal ovary development in monkeys, identifying key cellular processes and gene expression patterns in germ cells.

The paper uses single-cell RNA sequencing to analyze female germ cell development in mice, identifying seven clusters and uncovering Dpy30's role in meiosis initiation.

This study shows CDC6 is essential for G2 arrest and regulates spindle assembly and metaphase-to-anaphase transition in mouse oocytes.

This study shows that METTL14 is essential for mouse post-implantation development by promoting epiblast maturation from naive to primed state.