Author

Xukun Lu

Center for Life SciencesORCID 0000-0003-1122-2840Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Lei LiiD· 2 shared Qing‐Yuan SuniD· 2 shared Zhen‐Bo WangiD· 2 shared Zheng‐Hui ZhaoiD· 2 shared Bofeng LiuiD· 1 shared Fang-Nong LaiiD· 1 shared Feng Kong· 1 shared Geng AniD· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersDevelopmental Biology

Lei LiORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NR5A2 connects genome activation to the first lineage segregation in early mouse development

Fang-Nong Lai, Lijia Li, Xiaoyu Hu, Bofeng Liu, Ziqi Zhu, Ling Liu, Qiang Fan, Huabin Tian, Kai Xu, Xukun Lu, Qing Li, Feng Kong, Lijuan Wang, Zili Lin, Hongyu Deng, , Wei Xie

This study identifies NR5A2 as a key regulator linking zygotic genome activation to the first lineage segregation in early mouse development.

bioRxiv · Nov 25, 2022 · PreprintDevelopmental Biology

SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing

Wenbo Liu, Xukun Lu, Zheng‐Hui Zhao, Ruibao Su, Qian-Nan Li Li, Yue Xue, Zheng Gao, Simin Sun, Wen‐Long Lei, Lei Li, Geng An, Hanyan Liu, Zhiming Han, Ying‐Chun Ouyang, Yi Hou, , Jianqiao Liu

This study shows that SRSF10 regulates alternative splicing in progenitor spermatogonia, essential for their expansion and spermatogenesis.

eLife · Oct 24, 2022Peer-reviewedDevelopmental Biology

Mettl14 is required for mouse post-implantation development by facilitating epiblast maturation

Tie‐Gang Meng, Xukun Lu, Lei Guo, Guan-Mei Hou, Xue‐Shan Ma, Qiannan Li, Lin Huang, Li‐Hua Fan, Zheng‐Hui Zhao, Xiang‐Hong Ou, Ying-Chun Ou Yang, Heide Schatten, Lei Li, Zhen‐Bo Wang, Qing‐Yuan Sun

This study shows that METTL14 is essential for mouse post-implantation development by promoting epiblast maturation from naive to primed state.

The FASEB Journal · Aug 15, 2018Peer-reviewedDevelopmental Biology