Heide Schatten

Maternal total sleep deprivation causes oxidative stress and mitochondrial dysfunction in oocytes associated with fertility decline in mice

Spatiotemporal and single-cell atlas to dissect cell lineage differentiation and regional specific cell types in mouse ovary morphogenesis

This study builds a spatiotemporal and single-cell atlas of mouse ovary development, identifying novel cell types and regulatory factors in ovarian differentiation.

SRSF2 is required for mRNA splicing and spermatogenesis

This study shows SRSF2 is essential for mRNA splicing and spermatogenesis, with its deletion causing infertility and disrupting key developmental processes.

Single cell RNA sequencing reveals regulation of fetal ovary development in the monkey (Macaca fascicularis)

This study uses single-cell RNA sequencing to analyze fetal ovary development in monkeys, identifying key cellular processes and gene expression patterns in germ cells.

Single cell RNA sequencing reveals the landscape of early female germ cell development

The paper uses single-cell RNA sequencing to analyze female germ cell development in mice, identifying seven clusters and uncovering Dpy30's role in meiosis initiation.

CDC6 regulates both G2/M transition and metaphase-to-anaphase transition during the first meiosis of mouse oocytes

This study shows CDC6 is essential for G2 arrest and regulates spindle assembly and metaphase-to-anaphase transition in mouse oocytes.

Mettl14 is required for mouse post-implantation development by facilitating epiblast maturation

This study shows that METTL14 is essential for mouse post-implantation development by promoting epiblast maturation from naive to primed state.