Cell BiologybioRxivPreprint
Temporal regulation of G2 phase avoids therapy-induced senescence caused by DNA replication stress-inducing drugs and provides synergistic cytotoxicity
Kentaro Nonaka, Takeshi Wakasa, Hiroaki Ochiiwa…·Makoto Iimori
This study shows that shortening the G2 phase enhances cell death from DNA replication stress-inducing drugs, regardless of p53 status.
DOI 10.64898/2026.05.06.723184