Author

Nicolas Fossat

The University of SydneyORCID 0000-0002-0161-6507Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Patrick TamiD· 3 shared Jane Q. J. Sun· 2 shared Madeleine DemuthiD· 2 shared Mark Evan GrahamiD· 2 shared Pierre OsteiliD· 2 shared Xiaochen FaniD· 2 shared Ashley J. WaardenbergiD· 1 shared David A.F. Loebel· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersDevelopmental Biology

Patrick TamORCID

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Author profile →

3 papers

Recent·Most cited

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

Xiaochen Fan, V. Pragathi Masamsetti, Jane Q. J. Sun, Kasper Engholm‐Keller, Pierre Osteil, Joshua B. Studdert, Mark Evan Graham, Nicolas Fossat, Patrick Tam

The paper identifies a TWIST1-chromatin regulatory module critical for neural crest cell differentiation and craniofacial patterning through protein interaction and perturbation studies.

eLife · Feb 8, 2021Peer-reviewedDevelopmental Biology

TWIST1 homodimers and heterodimers orchestrate lineage-specific differentiation

Xiaochen Fan, Ashley J. Waardenberg, Madeleine Demuth, Pierre Osteil, Jane Q. J. Sun, David A.F. Loebel, Mark Evan Graham, Patrick Tam, Nicolas Fossat

This study identifies TWIST1 homodimers and heterodimers with E-proteins as key regulators of lineage-specific differentiation, revealing their distinct roles in mesoderm, neural crest, and endoderm development.

Molecular and Cellular Biology · Mar 13, 2020Peer-reviewedDevelopmental Biology

Ularcirc: Visualisation and enhanced analysis of circular RNAs via back and canonical forward splicing

David T. Humphreys, Nicolas Fossat, Madeleine Demuth, Patrick Tam, Joshua W. K. Ho

Ularcirc detects and analyzes circular RNAs using a novel method to filter false positives and provides visualization tools for circRNA characterization.

Nucleic Acids Research · Aug 8, 2019Peer-reviewedBioinformatics