Madeleine Demuth

The paper uses single-cell transcriptomics to study vertebrate trunk formation, identifying signaling pathways that regulate notochord and tissue development in human pluripotent stem cells.

The paper identifies two distinct cis regulatory strategies used by CREs to translate graded Shh signaling into differential gene expression in neural progenitors.

This study identifies TWIST1 homodimers and heterodimers with E-proteins as key regulators of lineage-specific differentiation, revealing their distinct roles in mesoderm, neural crest, and endoderm development.

Ularcirc detects and analyzes circular RNAs using a novel method to filter false positives and provides visualization tools for circRNA characterization.