Daniel Castaño‐Díez

The paper identifies SNX12 as a retromer adaptor critical for HPV16 infection and shows how cargo-adaptor interactions specify retromer coat architecture through structural and functional analyses.

The paper uses multimodal imaging to study the dynamic structure of the exocyst complex during exocytosis, revealing its conformational changes and tethering mechanism.

Ice Finder uses few-shot learning to segment non-vitrified ice in tomography, improving domain generalization and processing speed.

The paper uses high-resolution imaging and biophysical methods to show that Lewy pathology in Parkinson's disease consists mainly of a crowded membranous medley of vesicles and dysmorphic organelles, with only a small fraction containing proteinaceous filaments.