Identification of novel human topoisomerase III beta inhibitors
Yasir Mamun, Somaia Haque Chadni, Ramanjaneyulu Rayala, Shomita Ferdous, Rudramani Pokhrel, Adel Nefzi, Prem P. Chapagain, Yuk‐Ching Tse‐Dinh
The paper identifies potential inhibitors of TOP3B using molecular dynamics and docking, showing that bemcentinib and its analogs inhibit TOP3B relaxation activity.
bioRxiv · Mar 18, 2025 · PreprintBiochemistry