Author
Florida International UniversityORCID 0000-0002-6558-6693Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Shomita Ferdous, Yasir Mamun, Thirunavukkarasu Annamalai…·Yuk‐Ching Tse‐Dinh
The paper identifies a potential hinge region in MtbTOP1 critical for conformational changes during DNA relaxation, showing that mutations disrupt enzyme activity.
Li Shen, Abigail R. Swoboda, Caitlynn Diggs…·Yuk‐Ching Tse‐Dinh
This study shows that Chlamydia trachomatis TopA, containing a SWIB domain, mediates DNA relaxation and is essential for bacterial growth and host interaction.
Yasir Mamun, Somaia Haque Chadni, Ramanjaneyulu Rayala…·Yuk‐Ching Tse‐Dinh
The paper identifies potential inhibitors of TOP3B using molecular dynamics and docking, showing that bemcentinib and its analogs inhibit TOP3B relaxation activity.