Takashi Sonoki

This paper shows that high-grade B cell lymphomas with MYC and BCL2 rearrangements originate from BCR-silenced follicular lymphoma cells that acquire IGL::MYC translocations, leading to resistance to CD79B-targeting therapy.

This study shows that hypomorphic Lig4 mutation in mice causes Th1-skewed intestinal inflammation under adaptive immunodeficiency.

This paper demonstrates the use of eR1-CreERT2 transgenic mice to target and study hematopoietic stem cells (HSCs) across developmental stages, revealing stage-specific phenotypes and disease outcomes.