Tsuneyasu Kaisho

This study identifies conventional dendritic cells type 1 (cDC1s) as critical for anti-tumor immunity in brain metastases, showing their unique role in promoting CD8+ T cell responses and enhancing immunotherapy efficacy.

This study shows that hypomorphic Lig4 mutation in mice causes Th1-skewed intestinal inflammation under adaptive immunodeficiency.

This study characterizes peritoneal exudate cells in liver cirrhosis patients using single-cell and bulk RNA sequencing, revealing shifts in immune cell populations and gene expression with disease severity.